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吕斌

  • 中文简历English resume
  • 姓名:吕斌
  • 职务:教授,博士生导师,省部共建环境与健康教育部重点实验室,环境与健康国家环保部重点实验室 国家环保部武汉环境医学研究所 副所长
  • 院系:环境医学研究所
  • 地址:湖北省武汉市航空路13号 430030
  • 电话:
  • 邮箱:lubin@mails.tjmu.edu.cn

 

研究方向

1、 新型抗菌材料制备及其安全性评价

2、 环境痕量污染物的暴露及其健康效应监测与评价

3、 环境污染物暴露与儿童生长发育关系的队列研究

 

 

主要学术兼职

中国生物医学工程学会生物医学传感技术分会副主任理事;

 

中国仪器仪表学会传感器学会理事;

 

 

教育经历

1985, 9~1990, 7 同济医科大学公共卫生学院妇幼卫生专业,医学学士

 

1996, 9~1999.6 同济医科大学环境医学研究所,环境卫生学,医学硕士

 

1999.9~2002.6 华中科技大学同济医学院,环境卫生学,医学博士

 

 

工作经历

1990.7~1996.8 广西玉林地区妇幼保健院,从事预防保健及临床医学工作

 

2002.7~今 华中科技大学同济医学院环境医学研究所工作

 

2003.11~2003.12 澳大利亚西悉尼大学,访问学者

 

2004.6~2004.9 加拿大Saskatchewan大学访问学者

 

2012.12 瑞典Lund大学访问学者

 

 

近年来完成和正在承担的主要课题 (均为课题负责人)

﹠基于分子识别纳米材料的磷酸化蛋白生物标记物检测方法21277054,国家自然科学基金,2013.1-2016.12

 

﹠基于分子识别荧光纳米微球的痕量环境激素在线检测系统,教育部博士点基金,2012.1-2014.12

 

﹠特异性吸附/生物降解一体膜高效去除水中痕量环境激素的基础研究。国家自然科学基金30972435,2009.1-2011.12

 

﹠ 环境中微量有机污染物的分离、分析技术。国家自然科学基金海外青年学者合作项目20728708,2008.1-2010.12

 

﹠基于荧光MIM的多种痕量真菌毒素检测系统30671764。国家自然科学基金,2007.1-2009.12

 

﹠ 基于二核苷酸MIP的DNA加合物检测系统20477013。国家自然科学基金,2005.1-2007.12

 

﹠基于分子印迹的蓝藻毒素快速传感系统30200061。国家自然科学基金,2003.1-2005.12

 

﹠基于多功能纳米材料的艾滋病新型诊断技术研究,湖北省公益项目2014BCB049,2014.1-2015.12,纵向

 

﹠重金属和环境激素联合暴露对儿童神经系统发育的影响,湖北省卫生和计划生育委员会重点项目WJ2015MA026,2015.3-2017.3,纵向

 

﹠ 荆江航道整治工程对水环境质量影响的研究,交通运输部长江航道局科研项目2015010,2014.5-2015.11,纵向

 

﹠ 人工抗体快速检测和去除环境和食品中痕量雌二醇。湖北省卫生厅,2004.1-2006.12。

 

﹠ A novel human hepatic cell based system to monitor environmental carcinogens in real time. International Union Against Cancer. 2004.6-2004.9

 

 

奖励

教育部新世纪优秀人才支持计划,2006年 (No. NCET-06-0640)

 

吕斌、朱丽华、张敬东、唐和清、石云、王楠。 痕量环境致癌物暴露监测与控制。教育部高等学校科学研究优秀成果奖,自然科学二等奖,2009

 

吕斌、石云、江明、梅素容、侯长荣。痕量环境激素暴露及其健康损害的检测与评价研究。湖北省科学技术奖,自然科学三等奖,2008.

 

 

专利

吕斌、伍雅婷、叶磊。一种荧光材料的制备方法和应用。国家发明专利号201110039691.2

 

吕斌、刘倩。一种亲和吸附生物降解膜及其制备方法。国家发明专利号201110395867.8

 

唐瑛、吕 斌、张梦、石云。一种人工抗体SPR芯片的制备和应用。国家发明专利:201310150407.8

 

吕斌、黄正、钟剑、张梦、石云。一种痕量内毒素的快速检测新方法和试剂盒。国家发明专利申请号201310075844.8

 

吕斌、王雪娟、刘燕婕、石云。一种检测乙酰甲胺磷检测的方法和试剂盒。国家发明专利申请号201410072679.5

 

吕斌、伍雅婷、夏胡、石云、刘燕婕。一种多巴胺衍生物及分子印迹聚合物制备方法和应用。国家发明专利申请号201410221419.X

 

吕斌、刘燕婕、刘飞、罗密芳、石云。一种抗病毒感染纳米材料的制备及应用。国家发明专利申请号201510387979.7

 

 

近年主编和参编书目

书稿
Wan YC, Ma HT, Lu B*. MIPs in Aqueous Environments. Adv Biochem Eng Biotechnol. 2015, 150:131-166(Bo Mattiasson, Lei Ye ,Ed. Springer).

 

教材
《卫生检疫学》,全国高等学校教材,国家卫生和计划生育委员会”十二五“规划教材,主编
《卫生化学》(第7版),全国高等学校教材,国家卫生和计划生育委员会”十二五“规划教材,参编

 

 

近年来发表的主要论文(已发表论文70多篇,SCI论文20多篇,H因子17)

1. F. Liu, Q. Liu, Y. Zhang, Y. Liu, Y. Wan, K. Gao, Y. Huang, W. Xia, H. Wang, Y. Shi , Z. Huang*, B. Lu*. Molecularly imprinted nanofiber membranes enhanced biodegradation of trace bisphenol A by Pseudomonas aeruginosa. Chem Eng J, 2015, 262: 989-998

 

 

2. Y. Wu, Y. Liu, X. Gao, K. Gao, H. Xia, M. Luo, X. Wang, L. Ye,, Y. Shi*, B Lu*. Monitoring bisphenol A and its biodegradation in water using a fluorescent molecularly imprinted chemosensor. Chemosphere, 2015,119: 515-523

 

3. Y. Wu, Y. Zhang , M. Zhang, F. Liu, Y. Wan, Z. Huang, L. Ye, Q .Zhou, Y. Shi, B Lu*. Selective and simultaneous determination of trace bisphenol A and tebuconazole in vegetable and juice samples by membrane-based molecularly imprinted solid-phase extraction and HPLC. Food Chem, 2014, 164: 527-535

 

4. D Zheng, N Wang, X Wang, Y Tang, L Zhu, Z Huang, H Tang, Y Shi, Y Wu, M Zhang, B Lu*. Effects of the interaction of TiO2 nanoparticles with bisphenol A on their physicochemical properties and in vitro toxicity. J. Hazard. Mater. 2012, 199-200:426-432

 

5. Y Xie, H Li, L Wang, Q Liu, Y Shi , H Zheng, M Zhang, Y Wu, B Lu*. Molecularly imprinted polymer microspheres enhanced biodegradation of bisphenol A by acclimated activated sludge. Water Res, 2011, 45: 1189-1198

 

6. Y Shi, D Peng, C Shi, X Zhang, Y Xie, B Lu*. Selective determination of trace 17beta-estradiol in dairy and meat samples by molecularly imprinted solid-phase extraction and HPLC. Food Chem, 2011,126: 1916-1925

 

 

7. Y Shi, J Zhang, M Jiang, L Zhu, H Tan, B Lu*. Synergistic Genotoxicity Caused by Low Concentration of Titanium Dioxide Nanoparticles and p,p’-DDT in Human Hepatocytes. Environ Mol Mutagen, 2010, 51:192-204

 

8. M Jiang, Y Shi, R Zhang, C Shi, Y Peng, Z Huang, B Lu*. Selective molecularly imprinted stationary phases for Bisphenol A analysis prepared by modified precipitation polymerization. J. Sep. Sci. 2009, 32, 3265 – 3273

 

9. Y Shi, X-W Cao, F Tang, H-R Du, Y-Z Wang, X-Q Qiu, H-P Yu, B Lu*. In Vitro Toxicity of Surface Water Disinfected by Different Sequential Treatments. Water Res,2009,43: 218-228

 

10. Y Jin, M Jiang, Y Shi, Y L, Y Peng, K Dai, B Lu*. Narrowly Dispersed Molecularly Imprinted Microspheres Prepared by a Modified Precipitation Polymerization Method. Anal Chim Acta, 2008, 612: 105-113.

 

11. Y Lin, Y Shi, M Jiang, Y Jin, Y Peng, B Lu*, K Dai. Removal of phenolic estrogen pollutants from different sources of water using molecularly imprinted polymeric microspheres, Environ. Pollut. 2008, 153:483-491

 

12. M Hu, M Jiang, P Wang, S Mei, Y Lin, X Hu, Y Shi, Bin Lu*, K Dai. Selective Solid-Phase Extraction of Tebuconazole in Biological and Environmental Samples Using Molecularly Imprinted Polymers. Anal Bioanal Chem, 2007,387:1007-1016

 

13. Hou, CR; Lu, B* ; Lu, ZX ; Qin, SL. Association of health-related quality of life with health examination and lifestyles of government managers in China. J HUST-Med. Sci,2007, 27: 343-348

 

14. M Jiang, J Zhang, S Mei, Y Shi, L Zou, Y Zhu, K Dai, B Lu*. Direct Enrichment and High Performance Liquid Chromatography Analysis of Ultra-trace Bisphenol A in Water Samples with Narrowly Dispersible Bisphenol A Imprinted Polymeric Microspheres Column. J Chromatogr A, 2006,1110:27-34.

 

15. J Zhang, M Jiang, L Zou, D Shi, S Mei, Y Zhu, Y Shi, K Dai, B Lu*. Selective Solid-Phase Extraction of Bisphenol A Using Molecularly Imprinted Polymers and Its Application in Biological and Environmental Samples. Anal Bioanal Chem, 2006,385: 780-786

 

16. B Lu*, S Wu, Y Shi, R Zhang, L Zou, S Gao, M Lin, Y Zhou. Toxoplasma gondii: Expression Pattern and Detection of Infection Using Full-Length Recombinant P35 Antigen. Experimental Parasitology, 2006, 113: 83-90.

 

17. Y Shi, J Zhang D Shi, M Jiang, Y Zhu, S Mei, Y Zhou, K Dai, Bin Lu* . Selective Solid-Phase Extraction of Cholesterol Using Molecularly Imprinted Polymers and Its Application in Different Biological Samples. J. Pharm. Biomed. Anal, 2006, 42: 549-555.

 

18. B Lu; S Xu; Z Chen; Y Zhou. Rapid drug susceptibility test of mycobacterium tuberculosis by bioluminescence sensor. Proceedings SPIE, 2001, 4414: 133-36

 

19. S Xu, M He, H Yu, X Wang, X Tan, B Lu, X Sun, Y Zhou, Q Yao, Y Xu, Z Zhang. Bioluminescent method for detecting telomerase activity. Clin Chem 2002,48:1016-20

 

20. S Xu, M He, H Yu, X Cai, X Tan, B Lu, B Shu. A quantitative method to measure telomerase activity by bioluminescence connected with telomeric repeat amplification protocol. Anal Biochemistry, 2001, 299:188-93

 

21. H Yu, S Xu, L Li, L Si, X Cai, W Lu , B Lu, Y Su, Y Li. Cyclooxygenase-2 expression in squamous dysplasia and squamous cell carcinoma of the esophagus. Cancer lett, 2003, 198: 193-201 H