首页 > 师资队伍 > 院系教师 >

徐顺清

  • 中文简历English resume
  • 姓名:徐顺清
  • 职务:副院长,教授,博士生导师
  • 院系:环境医学研究所
  • 地址:湖北省武汉市航空路13号 430030
  • 电话:
  • 邮箱:xust@hust.edu.cn

 

      徐顺清,1966年3月出生,博士,教授,博士生导师。华中科技大学国家重点学科劳动卫生与环境卫生学科带头人,国家百千万人才工程、长江学者特聘教授、教育部新世纪优秀人才支持计划及国务院政府特殊津贴获得者。1988年毕业于湖南医科大学,硕博连读,1993年在同济医科大学获预防医学博士学位,先后多次在德国Max-Planck生物化学研究所和Tuebingen大学进行访问研究。长期以来从事环境污染对人体健康危害的机制和生物标志物研究。先后承担国家自然科学基金重大项目子课题1项、重点项目1项、海外青年学者合作基金项目1项、面上项目5项,国家863计划课题2项,环保公益项目2项以及其他省部级课题10余项。在Clin Chem, Environ Health Perspect,Nanomed-Nanotech, Biosensor Bioelectron,Anal Chem等相关领域权威期刊以通讯作者发表SCI论文60余篇,SCI 他引800多次。主要学术兼职有:第十、十一届国家自然科学基金委化学学部环境化学学科二审专家,中国环境科学学会环境医学与健康分会副主任委员,中国仪器仪表学会传感器分会常务理事,中国预防医学杂志编委,华中科技大学学报(医学版)编委,生态毒理学报编委等。三项成果获得省部级二等奖。

 

主要研究领域

环境流行病学、环境毒理学

 

环境流行病学主要负责的科研项目

1. 1环境内分泌干扰物胚胎期暴露对糖脂代谢疾病发育起源的影响及健康风险研究。国家自然科学基金重点项目(21437002),2015.1—2019.12, 350万元。

 

2. 重大疾病致病机理及防治的基础问题研究,国家重点基础研究发展计划(973计划)项目(2012CB722400),2012.1—2013.12,1324万元。

 

3. 食品中类雌激素的筛查及其致代谢综合症的风险和机制研究,国家自然科学基金重点项目(81030051),2011.1-2014.12,210万元。

 

4. 淮河流域环境污染与癌症风险评价及环境健康管理体系研究,环境保护部淮河流域癌症综合专项,2009.1-2015.12,440万元。

 

5. 基于健康风险评价环境空气铅质量标准限值制定方法研究,环境保护公益性行业科研专项(201309048),2013.1-2015.12,564万元。

 

代表性论著

1. Wei Xia, Xiaofu Du, Bin Zhang, Yuanyuan Li, Bryan A. Bassig, Aifen Zhou, Youjie Wang, Chao Xiong, Zhengkuan Li, Yuanxiang Yao, Jie Hu, Yanqiu Zhou, Qi Wang, Juan Liu, Weiyan Xue, Yue Ma, Xinyun Pan, Yang Peng, Tongzhang Zheng, and Shunqing Xu*. A Case–Control Study of Prenatal Thallium Exposure and Low Birth Weight in China. Environ Health Perspect. DOI:10.1289/ehp.1409202.

 

2. Ying Jiang , Wei Xia, Jie Yang, Yingshuang Zhu, Huailong Chang, Juan Liu, Wenqian Huo, Bing Xu , Xi Chen, Yuanyuan Li, Xu S*. BPA-induced DNA hypermethylation of the master mitochondrial gene PGC-1alpha contributes to cardiomyopathy in male rats. Toxicology. 2015 Mar 2;329:21-31.

 

3. Jie Wei, Xia Sun, Yajie Chen, Yuanyuan Li, Liqiong Song, Zhao  Zhou, Bing Xu, Yi Lin, Shunqing Xu *. Perinatal exposure to bisphenol A exacerbates nonalcoholic steatohepatitis-like phenotype in male rat offspring fed on a high-fat diet. J Endocrinol. 2014 Sep;222(3):313-25.

 

4. Genqi Li, Huailong Chang, Wei  Xia, Zhenxing Mao, Yuanyuan Li, Shunqing Xu* . F0 maternal BPA exposure induced glucose intolerance of F2 generation through DNA methylation change in Gck. Toxicol Lett. 2014 Aug 4;228(3):192-9.

 

5. Ying Jiang , Wei Xia, Yingshuang Zhu, Xiaocui  Li, Danqi Wang, Juan Liu, Huailong Chang, Genqi Li, Bing Xu , Xi Chen, Yuanyuan Li, Shunqing Xu *. Mitochondrial dysfunction in early life resulted from perinatal bisphenol A exposure contributes to hepatic steatosis in rat offspring. Toxicol Lett. 2014 Jul 15;228(2):85-92.

 

6. Hongyu Zhang, Weiyan Xue,Yuanyuan Li, Yue Ma, Yingshuang Zhu, Wenqian Huo, Bing Xu, Wei Xia, Shunqing Xu *. Perinatal exposure to 4-nonylphenol affects adipogenesis in first and second generation rats offspring. Toxicol Lett. 2014 Mar 3;225(2):325-32.

 

7.  Wei Xia, Ying Jiang, Yuanyuan Li, Yanjian Wan, Juan Liu, Yue Ma, Zhenxing Mao, Huailong Chang, Genqi Li, Bing Xu, Xi Chen, Shunqing Xu*. Early-Life Exposure to Bisphenol A Induces Liver Injury in Rats Involvement of Mitochondria-Mediated Apoptosis. PLoS One. 2014 Feb 28;9(2):e90443. (IF=3.534)

 

8. Yue Ma, Wei Xia, Danqi Wang, Yanjian Wan, Bing Xu, Xi Chen, Yuanyuan Li, Shunqing Xu*. Hepatic DNA methylation modifications in early development of rats resulting from perinatal BPA exposure contribute to insulin resistance in adulthood. Diabetologia. 2013, 56(9):2059-67.

 

9.  Liqiong Song, Wei Xia, Zhao Zhou, Yi Li, Jie Wei, Zhengzheng Wei, Bing Xu, Jie Shen, Weiyong Li, Shunqing Xu*. Low-level phenolic estrogen pollutants impair islet morphology and β-cell function in isolated rat islets. J Endocrinol, 2012, 215(2):303-11.

 

10. Tian Chen, Ling Zhang, JunquanYue, Ziquan Lv, Wei Xia, Yanjian Wan, Yuanyuan Li, Shunqing Xu*. Prenatal PFOS exposure induces oxidative stress and apoptosis in the lung of rat off-spring. Reprod Toxicol, 2012, 33(4):538-45.

 

11. Zhengzheng Wei, Liqiong Song, Jie Wei, Tian Chen, Jun Chen, Yi Lin, Wei Xia, Bing Xu, Xuguang Li, Xi Chen, Yuanyuan Li, Shunqing Xu*. Maternal exposure to di-(2-ethylhexyl)phthalate alters kidney development through the renin-angiotensin system in offspring. Toxicol Lett, 2012, 212(2):212-21.

 

12. Wei Xia, Yanjian Wan, Xianliang Wang, Yuanyuan Li, Wenjie Yang, Chunxiang Wang, Shunqing Xu*. Sensitive bioassay for detection of PPARα potentially hazardous ligands with gold nanoparticle probe. J Hazard Mater, 2011, 192(3):1148-54.

 

13. Yi Lin, Jie Wei, Yuanyuan Li, Jun Chen, Zhao Zhou, Liqiong Song, Zhengzheng Wei, Ziquan Lv, Xi Chen, Wei Xia, Shunqing Xu*. Developmental exposure to di(2-ethylhexyl) phthalate impairs endocrine pancreas and leads to long-term adverse effects on glucose homeostasis in the rat. Am J Physiol Endocrinol Metab, 2011, 301(3):E527-38.

 

14. Jie Wei, Yi Lin, Yuanyuan Li, Chenjiang Ying, Jun Chen, Liqiong Song, Zhao Zhou, Ziquan Lv, Wei Xia, Xi Chen, Shunqing Xu*. Perinatal exposure to bisphenol A at reference dose predisposes offspring to metabolic syndrome in adult rats on a high-fat diet. Endocrinology, 2011, 152(8):3049-61.

 

15. Wei Xia, Yanjian Wan, Yuanyuan Li, Huaicai Zeng, Ziquan Lv, Gengqi Li, Zhengzheng Wei, Shunqing Xu*. PFOS prenatal exposure induce mitochondrial injury and gene expression change in hearts of weaned SD rats. Toxicology, 2011, 282(1-2):23-9.

 

16. Tian Chen, Wenjie Yang, Yuanyuan Li, Xi Chen, Shunqing Xu*. Mono-(2-ethylhexyl) phthalate impairs neurodevelopment: inhibition of proliferation and promotion of differentiation in PC12 cells. Toxicol Lett, 2011, 201(1):34-41.

 

17. Yuanyuang Li, Hermann J Schluesene, Shunqing Xu*, Gold nanoparticle-based biosensors. Gold bulletin, 2010, 43(1): 29-41.

 

18. Yan-jian Wan, Yuan-yuan Li, Wei Xia, Jun Chen, Zi-quan Lv, Huai-cai Zeng, Ling Zhang, Wen-jie Yang, Tian Chen, Yi Lin, Jie Wei, Shun-qing Xu*. Alterations in tumor biomarker rGSTP gene methylation patterns induced by prenatal exposure to PFOS. Toxicology, 2010, 274: 57-64.

 

19.  Wei Xia, Yuanyuan Li, Yanjian Wan, Tian Chen, Jie Wei, Yi Lin, Shunqing Xu*. Electrochemical biosensor for estrogenic substance using lipid bilayers modified by Au nanoparticles. Biosens and Bioelectron, 2010, 25(10):2253-8.