Dr. Wei Yang is a Lecturer of Department of Nutrition and Food Hygiene, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology (HUST). He graduated with a major in Sports Medicine in Wuhan Sports University from 2000 to 2007 (Bachelor and Master) and received his PhD degree in 2012 from School of Public Health, Tongji Medical College, Huazhong University of Science and Technology. He also was a Post-Doc in Medical College, Tuebingen University, Germany (2012.10-2014.05) and Department of pathophysiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology (2014.09-2016.10), respectively. Dr. Yang’s research is mainly focused on nutritional epidemiology and prevention of type 2 diabetes, gene-nutrients interactions and risk of type 2 diabetes, biological significance of heme oxygenase-1, autophagy, non-coding RNA and toxic mechanism of Deoxynivalenol (DON) in human samples or toxic effect in different animal models and cell lines. He has published 15 original papers in SCI-collected journals as First author or Corresponding author, including Archives of Toxicology, Cellular Physiology and Biochemistry, Food and Chemical Toxicology, European Journal of Endocrinology and Journal of Applied Toxicology

Education

2000/09-2004/06  Bachelor’s Degree of Education The Faculty of Sports Medicine Wuhan Sports University

2004/09-2007/06  Master’s Degree of Education The Faculty of Sports Medicine Wuhan Sports University

2009/09-2012/06  Doctoral Degree of Medicine Department of Nutrition and Food Hygiene School of Public Health, Tongji Medical College, Huazhong University of Science and Technology

Language: Chinese, English, German

Work Experience

2012/10-2014/05  Post-Doc Training BG Unfall Clinik, Medical College Tuebingen University, Germany

2014/09-2016/10  Lecturer, Post-Doc Training Department of pathophysiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology

2016/11-now  Lecturer Department of Nutrition and Food Hygiene School of Public Health, Tongji Medical College, Huazhong University of Science and Technology

Present Active Research Funding (As the principal investigator)

1. National Natural Science Foundation of China (NSFC81502811, 180000 RMB)

2. China Postdoctoral Science Foundation (2015M572154, 50000 RMB)

3. Anqi research Fund (AF2017004, 300000 RMB)

4. Natural Science Foundation of Hubei Province (2017, 50000 RMB)

Career Goals

1. Nutritional epidemiology and prevention of AD, PD, obesity and type 2 diabetes.

2. Gene-environment interactions, biomarkers with AD, PD, type 2 diabetes.

3. Exposure levels of mycotoxin (DON) in Chinese population and risk assessment.

4. Toxic mechanism of DON-induced hepatotoxicity and metabomomics.

5. HO-1 regulates Autophagy in diabetes population and under toxic factors exposure.

6. Gut microbiota, non-coding RNA and aging.

Selected Publications in SCI journals (*First author, Co-first author and Corresponding author)

1. Yu M, Chen L, Peng Z, Nüssler AK, Wu Q, Liu L, Yang W. Mechanism of deoxynivalenol effects on the reproductive system and fetus malformation: Current status and future challenges. Toxicol In Vitro. 2017 Jun;41:150-158.

2. Yu M, Chen L, Peng Z, Wang D, Song Y, Wang H, Yao P, Yan H, Nüssler AK, Liu L, Yang W*. Embryotoxicity Caused by DON-Induced Oxidative Stress Mediated by Nrf2/HO-1 Pathway. Toxins (Basel). 2017 Jun 9;9(6).

3. Tang J, Yu Y, Yang W*. Long noncoding RNA and its contribution to autism spectrum disorders. CNS Neurosci Ther. 2017 Aug;23(8):645-656.

4. Chen L, Peng Z, Nüssler AK, Liu L, Yang W. Current and prospective sights in mechanism of deoxynivalenol-induced emesis for future scientific study and clinical treatment. J Appl Toxicol. 2017 Jul;37(7):784-791.

5. Peng Z, Chen L, Xiao J, Zhou X, Nüssler AK, Liu L, Liu J, Yang W*. Review of mechanisms of deoxynivalenol-induced anorexia: The role of gut microbiota. J Appl Toxicol. 2017 Sep;37(9):1021-1029.

6. Peng Z, Liangkai C, Nüssler AK, Liu L, Wei Yang*. Current Sights for Mechanisms of DON-induced Hepatotoxicity and Prospective Views for Future Scientific Research: A Mini Review. J Appl Toxicol. 2016 Nov 09.

7. Chen L, Yu M, Wu Q, Peng Z, Wang D, Kuča K, Yao P, Yan H, Nüssler AK, Liu L, Yang W*. Gender and geographical variability in the exposure pattern and metabolism of deoxynivalenol in humans: a review. J Appl Toxicol. 2016 Jul 26.

8. Li P, Shan Z, Zhou L, Xie M, Bao W, Zhang Y, Rong Y, Yang W*, Liu L*. MECHANISMS IN ENDOCRINOLOGY: Parity and risk of type 2 diabetes: a systematic review and dose-response meta-analysis. Eur J Endocrinol. 2016 Nov;175(5):R231-45.

9. Tang J*, Yang W*, Ahmed NI, Ma Y, Liu HY, Wang JJ, Wang PX, Du YK, Yu YZ. Stressful Life Events as a Predictor for Nonsuicidal Self-Injury in Southern Chinese Adolescence: A Cross-Sectional Study. Medicine (Baltimore). 2016 Mar;95(9):e2637.

10. Yang W*, Fu J, Yu M, Wang D, Rong Y, Yao P, Nüssler AK, Yan H, Liu L. Effects of three kinds of curcuminoids on anti-oxidative system and membrane deformation of human peripheral blood erythrocytes in high glucose levels. Cell Physiol Biochem. 2015;35(2):789-802.

11. Yang W*, Burkhardt B, Fischer L, Beirow M, Bork N, Wönne EC, Wagner C, Husen B, Zeilinger K, Liu L, Nussler AK. Age-dependent changes of the antioxidant system in rat livers are accompanied by altered MAPK activation and a decline in motor signaling. EXCLI J. 2015 Dec 22;14:1273-90.

12. Wu QH*, Wang X*, Yang W*, Nüssler AK, Xiong LY, Kuča K, Dohnal V, Zhang XJ, Yuan ZH. Oxidative Stress-Mediated Cytotoxicity and Metabolism of Trichothecene T-2 toxin and Deoxynivalenol in Animals and Humans: An Update. Arch Toxicol. 2014 Jul;88(7):1309-26.

13. Yang W*, Yu M, Fu J, Bao W, Wang D, Hao L, Yao P, Nüssler AK, Yan H, Liu L. Deoxynivalenol induced oxidative stress and genotoxicity in human peripheral blood lymphocytes. Food Chem Toxicol. 2014 Feb;64:383-96.

14. Yang W*, Fu J, Xiao X, Yan H, Bao W, Wang D, Hao L, Nussler AK, Yao P, Liu L. Quinocetone triggers oxidative stress and induces cytotoxicity and genotoxicity in human peripheral lymphocytes of both genders. J Sci Food Agric. 2013 Apr;93(6):1317-25.

15. Yang W*, Fu J, Yu M, Huang Q, Wang D, Xu J, Deng Q, Yao P, Huang F, Liu L. Effects of flaxseed oil on anti-oxidative system and membrane deformation of human peripheral blood erythrocytes in high glucose level. Lipids Health Dis. 2012 Jul 8;11:88.

Abstracts and Presentations

1. World Life Science Conference 2016. Dietary Phytochemicals Decelerate Aging and Prolong Longevity: Current Sights and Future Challenge. Invited Oral Presentation, Beijing, China.

2. EFFoST International Conference 2010 and 2011. Quinocetone triggers oxidative stress and induces cytotoxicity and genotoxicity in human peripheral lymphocytes of both genders. Poster Presentation. Berlin, Germany and Florence, Italy.