Education and Professional Experience
2005/08-2009/06: B.S. in Computational Biology, National University of Singapore, Singapore
2009/08-2014/12: Ph.D. in Bioinformatics, University of Michigan, Ann Arbor, MI, U.S.A.
2015/05-2018/06: Research Fellow, Duke-NUS Medical School, Singapore
2018/08 till present: Associate Professor, School of Public Health, Tongji Medical School, Hwazhong University of Science and Technology, Wuhan, China
Research Interests
Applying integrative analysis to multi-omics data, in order to gain better understanding of the dysregulation of molecular mechanisms underpinning complex diseases, such as cancer.
Publications
Thekkeparambil Chandrabose S, Sriram S, Subramanian S, Cheng S, Ong WK, Rozen S, Kasim NHA, Sugii S (2018). Amenable epigenetic traits of dental pulp stem cells underlie high capability of xeno-free episomal reprogramming. Stem Cell Research & Therapy 9(1):68
Cheng S and Brooks CL III (2015). Protein-protein interfaces in viral capsids are structurally unique. Journal of Molecular Biology 427: 3613-24.
Cheng S, Zhang Y and Brooks CL III (2015). PCalign: a method to quantify physico-chemical similarity of protein-protein interfaces. BMC Bioinformatics 16: 33.
Cheng S and Brooks CL III (2013). Capsid proteins are segregated in structural fold space. PLoS Computational Biology 9: e1002905.
Strunk BS, Loucks CR, Su M, Vashisth H, Cheng S, Schilling J, Brooks CL III, Karbstein K, Skiniotis G (2011). Ribosome assembly factors prevent premature translation initiation by 40S assembly intermediates. Science 333(6048):1449-53.