华中科技大学公共卫生学院, 副教授,博士生导师
一、主持或参加科研项目（课题）情况（按时间倒序排序）:
⒈ 武汉市科技计划项目，2020020601012246，衰老细胞启动细胞竞争诱导凋亡在糖尿病肾病中的作用及榭皮素干预，2020/08-2022/12，50万，在研，主持。
⒉ 国家自然科学基金面上项目，81872619，Rab7介导的线粒体自噬和外泌体在
酒精性肝铁过载的协同机制及槲皮素干预研究，2019/01-2022/12，在研，主持。
3. 2018年国家重点研发计划，2018YFC1604003，食品安全大数据关键技术研究
课题“食品安全大数据智能应用技术研究”，2018/12-2021/12，在研，子课题负责人。
4. 安琪营养基金科研项目资助，20191685，布拉氏酵母对儿童急性腹泻的随机双盲安慰剂对照临床研究，2019/7-2021/7，在研，主持。
5. 湖北省自然科学基金面上项目，2018CFB480，应用蛋白质组学分析Frataxin缺失对酒精性肝线粒体自噬的作用及其机制，2018/01-2019/12，结题，主持。
6. 国家自然科学基金委员会，青年基金，81402673，FOXO3-Frataxin介导的肝脏线粒体酒精性损伤及槲皮素干预机制，2015/01-2017/12，已结题，主持。
7. 中国博士后科学基金，第56批中国博士后基金面上项目，130324，ALD中Parkin
和受体介导的线粒体自噬失衡及槲皮素干预，2014/01-2015/12，已结题,主持。
二、代表性论著
(1) Li Chen, Xingzhu Yin, Ying Zhao, Huimin Chen, Tianqi Tan, Ping Yao, Yuhan Tang*. Biological ageing and the risks of all-cause and cause-specific mortality among people with diabetes: a prospective cohort study. J Epidemiol Community Health. 2022, doi: 10.1136/jech-2022-219142.
(2) Li Chen, Ying Zhao, Fangqu Liu, Huimin Chen, Tianqi Tan, Ping Yao, Yuhan Tang*. Biological aging mediates the associations between urinary metals and osteoarthritis among U.S. adults. BMC Med. 2022, 20(1): 207.
(3) Yuhan Tang#, Yanyan Xu, Peiyi Liu, Cheng Liu, Rong Zhong, Xiao Yu, Lin Xiao, Min Du, Ling Yang, Jing Yuan, Youjie Wang, Weihong Chen, Sheng Wei, Yuan Liang, Xiaomin Zhang, Tangchun Wu, Meian He#, Xiaoping Miao#, Ping Yao# . No Evidence for a Causal Link between Serum Uric Acid and Nonalcoholic Fatty Liver Disease from the Dongfeng-Tongji Cohort Study.Oxid Med Cell Longev. 2022, 2022: 6687626.
(4) Wan Zhang, Shu-Fen Peng, Li Chen, Hui-Min Chen , Xue-Er Cheng, Yu-Han Tang*.Association between the Oxidative Balance Score and Telomere Length from the National Health and Nutrition Examination Survey 1999-2002. Oxid Med Cell Longev. 2022, 2022:1345071.
(5) Chen L, Sun Q, Peng S, Tan T, Mei G, Chen H, Zhao Y, Yao P, Tang Y*. Associations of blood and urinary heavy metals with rheumatoid arthritis risk among adults in NHANES, 1999-2018. Chemosphere. 2022, 289:133147. (IF: 7.086)
(6) Shufen Peng, Huimin Chen, Li Chen, Guang Yang, Jingjing Liu, Xueer Cheng, Yuhan Tang*. Beyond Isocitrate Dehydrogenase Mutations: Emerging Mechanisms for the Accumulation of the Oncometabolite 2-Hydroxyglutarate. Chem Res Toxicol. 2022,35(2):115-124. (IF: 3.739)
(7) Wan Zhang , Shu-Fen Peng, Li Chen, Hui-Min Chen, Xue-Er Cheng, Yu-Han Tang*. Association between the Oxidative Balance Score and Telomere Length from the National Health and Nutrition Examination Survey 1999-2002. Oxid Med Cell Longev. 2022 , 2022:1345071. (IF: 6.543)
(8) Tang Y, Xu Y, Liu P, Liu C, Zhong R, Yu X, Xiao L, Du M, Yang L, Yuan J, Wang Y, Chen W, Wei S, Liang Y, Zhang X, Wu T, He M, Miao X, Yao P. No Evidence for a Causal Link between Serum Uric Acid and Nonalcoholic Fatty Liver Disease from the Dongfeng-Tongji Cohort Study. Oxid Med Cell Longev. 2022, 2022:6687626. (IF: 6.543)
(9) Lin Xiao, Gang Luo, Hongxia Li, Ping Yao*, Yuhan Tang*. Dietary iron overload mitigates atherosclerosis in high-fat diet-fed apolipoprotein E knockout mice: Role of dysregulated hepatic fatty acid metabolism. BBA- Mol Cell Biol L. 2021,1866(10):159004. (IF: 4.698)
(10) Li Chen, Jing Liu, Guibin Mei, Huimin Chen, S Peng, Ying Zhao, Ping Yao, Yuhan Tang*. Quercetin and non-alcoholic fatty liver disease: A review based on experimental data and bioinformatic analysis. Food Chem Toxicol. 2021, 154:112314. ( IF: 6.02)
(11) Hongxia Li, Lin Xiao, Hui He, Hongmei Zeng, Jingjing Liu, Chunjie Jiang, Guibin Mei, Jiasheng Yu, Hao Chen, Ping Yao*, Yuhan Tang*. Quercetin Attenuates Atherosclerotic Inflammation by Inhibiting Galectin-3-NLRP3 Signaling Pathway. Mol Nutr & Food Res. 2021, 65(15):e2000746.（IF:5.91）
(12) Li Chen, Guibin Mei, Chunjie Jiang, Xueer Cheng, Dan Li, Ying Zhao, Hunmin Chen, C Wan, Ping Yao, Chao Gao*, Yuhan Tang*. Carbon monoxide alleviates senescence in diabetic nephropathy by improving autophagy. Cell Prolif. 2021, 54(6):e13052. (IF:6.83)
(13) Jingjing Liu; Hui He; Jing Wang; Xiaoping Guo;Hongkun Lin;Huimin Chen;Chunjie Jiang; Li Chen;Ping Yao*; Yuhan Tang*; Oxidative stress-dependent frataxin inhibition mediated alcoholic hepatocytotoxicity through ferroptosis,Toxicology, 2020, 445: 152584.
(14) Xinhong Zhu; Ting Xiong;Peiyi Liu; Xiaoping Guo; Lin Xiao; Feng Zhou;YuhanTang*;Ping Yao*; Quercetin ameliorates HFD-induced NAFLD bypromotinghepatic VLDL assembly and lipophagy via the IRE1a/XBP1s pathway, Food Chem Toxicol, 2018, 114: 52-60.
(15) Lin Xiao; Gang Luo;Yuhan Tang*; Ping Yao*; Quercetin and ironmetabolism: What we know and what we need to know, Food Chem Toxicol, 2018, 114: 190-203.
(16) Peiyi Liu; Hongkun Lin; Yanyan Xu; Feng Zhou; Jing Wang; JingjingLiu; XinhongZhu; Xiaoping Guo; YuhanTang*; Ping Yao*;Frataxin-Mediated PINK1-Parkin-Dependent Mitophagy in Hepatic Steatosis: The Protective Effects of Quercetin,Mol Nutr &Food Res, 2018,62(16):e1800164.
(17) YanyanLi; Chen M;YanyanXu;Xiao Yu;Ting Xiong;Min Du;Jian Sun; LiegangLiu;YuhanTang*;Ping Yao*;Iron-mediated Lysosomal Membrane Permeabilization in Ethanol Induced Hepatic Oxidative Damage and Apoptosis: Protective Effects of Quercetin, Oxid Med Cell Longev, 2016, 2016: 4147610.
(18) Chao Gao;Yang Liu;ChunjieJiang;Liang Liu;Juan Li;Dan Li;Xiaoping Guo;Zhu Wang;YuexinYang;LiegangLiu;Ping Yao; YuhanTang*;Intensive Running Enhances NF-κB Activity in the Mice Liver and the Intervention Effects of Quercetin,Nutrients, 2020, 12:2770.
(19) Lin Xiao; Liang Liu; Xiaoping Guo; Shanshan Zhang; Jing Wang; Feng Zhou; LiegangLiu; YuhanTang*; Yao P*; Quercetin attenuates high fat diet-induced atherosclerosis inapolipoprotein Eknockout mice: A critical role of NADPH oxidase, Food Chem Toxicol, 2017, 105: 22-23.
(20) YuhanTang#; YanyanLi; Haiyan Yu; Chao Gao; Liang Liu; Shaodan Chen;Mingyou Xing; Liegang Liu; Ping Yao*; Quercetin prevents ethanol-induced iron overload by regulating hepcidin through the BMP6/SMAD4 signaling pathway, J Nutr Biochem,2014, 25(6):675-82.
(21) YuhanTang;Juan Li; Chao Gao; YanyanXu; YanyanLi; Xiao Yu; Jing Wang; LiegangLiu; Ping Yao*;Hepatoprotective Effect of Quercetin on Endoplasmic Reticulum Stress andInflammation after Intense Exercise in Mice through Phosphoinositide 3-Kinaseand Nuclear Factor-Kappa B, Oxid Med Cell Longev, 2016,2016:8696587.
(22) Xiao Yu; YanyanXu; Shanshan Zhang; Jian Sun; PeiyiLiu; Lin Xiao; YuhanTang*; LiegangLiu; Ping Yao*;Quercetin Attenuates Chronic Ethanol-Induced Hepatic Mitochondrial Damagethrough Enhanced Mitophagy,Nutrients, 2016, 8(1): 27.
(23) YuhanTang;YanyanLi; Haiyan Yu; Chao Gao; Liang Liu; MingyouXing; LiegangLiu; Ping Yao*;Quercetin attenuates chronic ethanol hepatotoxicity: implication of “free” iron uptake and release, Food Chem Toxicol, 2014, 67: 131-138.
(24) YuhanTang#;HongtaoTian#; YanruShi; Chao Gao; MingyouXing; Wei Yang; Wei Bao; Di Wang; LiegangLiu; Ping Yao*;Quercetin suppressed CYP2E1-dependent ethanol hepatotoxicity viadepleting heme pool and releasing CO,Phytomedicine, 2013, 20(8-9):699-704.
(25) YuhanTang#; Chao Gao#; MingyouXing; YanyanLi; LipingZhu; Di Wang; XuefengYang; LiegangLiu; Ping Yao*; Quercetin prevents ethanol-induced dyslipidemia and mitochondrialoxidative damage, Food Chem Toxicol, 2012, 50(5):1194-1200.
(26) YuhanTang; Chao Gao; YanruShi; LipingZhu; Hu XM; Di Wang; Liu Yang; XuefengYang; LiegangLiu; Ping Yao*; Quercetin attenuates ethanol-derived microsomal oxidative stress: Implication of haem oxygenase-1 induction,Food Chem, 2012,132(4):1769-1774.
(27) YuhanTang#; Jian Xu; Wei Qu; Xiaolin Peng; Peng Xin; Xuefeng Yang; Chenjiang Ying; XiufaSun; Liping Hao*; Resveratrol reduces vascular cell senescence through attenuation of oxidative stress by SIRT1/NADPH oxidase-dependent mechanisms, J Nutr Biochem, 2012, 23(11): 1410-1416.
三、参编教材或专著
1. 社区营养与健康管理，人民卫生出版社、124-136页，2020年12月，编委。
2. 真菌毒素污染与健康，湖北科技出版社、1-24，2021年12月，副主编。
四、获奖或社会服务
1. 武汉营养学会秘书长
2. 中国营养学会社区营养与健康管理分会常务委员
3. 唐玉涵(3/5); 植物黄铜诱导HO-1拮抗酒精性肝病的机制, 湖北省人民政府, 自然科学, 省部二等奖, 2014(刘烈刚;姚平;唐玉涵; 郝丽萍; 杨雪锋).
