Dr. MeixiaLu is an associate Professor ofEpidemiology and Statistic. Dr. Lu’s research is mainly focused on molecular epidemiology of head and neck squamous cell carcinoma (including genetics, epigenetics and interaction between environment andgene on cancer) and carcinogenesis and biomarkers of occupational and environmental related cancer. Dr. Lu is a member of Wuhan expert committee of prevention and control of poor vision in adolescent. She is also interested in comprehensive intervention model, early warning, and health management on poor vision of primary and middle school students.
Education
1992/09-1998/07 Bachelor’s Degree of Medicine
The Faculty of Preventive Medicine
Tongji Medical University
2001/09-2004/07 Master’s Degree of Medicine
Department of Epidemiology and Statistic
School of Public Health
Tongji Medical College
Huazhong University of Science and Technology
2004/09-2007/07 Doctoral Degree of Medicine
Department of Occupational and Environmental Health
School of Public Health
Tongji Medical College
Huazhong University of Science and Technology
Languages
Chinese, English
Work Experience
1998/09-2003/06 Assistant
Department of Epidemiology and Statistics
School of Public Health
Tongji Medical University
2003/07-2013/10 Lecturer
Department of Epidemiology and Statistics
School of Public Health
Tongji Medical College
Huazhong University of Science and Technology
2009/10-2010/10 Visiting scholar
Department of epidemiology,
MD Anderson Cancer Center, TEXAS, USA
2013/11- present Associate professor
Department of Epidemiology and Statistics
School of Public Health
Tongji Medical College
Huazhong University of Science and Technology
Studies and Previous Research Funding
1. Study of genetic variations in the cell senescence related genes and microRNAs with the risk of head and neck squamous cell carcinoma. Supported by funds from Natural Scientific Foundation of China 8137309，201/01/2014-12/30/2017 (PI)
2. Interactions between Haplotype of heat shock protein related genes and benzo(a)pyrene with the risk of lung cancer, Supported by funds from Youth foundation of National Natural Scientific Foundation of China 3050416，01/01/2006-12/30/2008, (PI)
3. Teaching reform of Epidemiology based on ability cultivation of critical thinking，Supported by funds from Educational reform Foundation of Hubei province，01/01/2016-12/30/2017 (PI)
4. The training program on HIV/AIDS prevention for juvenile druggers and delinquents, Supported by funds from Social Mobilization Fund of Prevention and Cure by China State Council Grants 05-Ⅱ-14，01/01/2005-12/30/2005 (PI)
5. HIV/AIDS prevention education and Voluntary Counseling and Testing in a women’s prison, Supported by funds from China Global Fund AIDS Program Office Round 3, 2007-NGS-34，01/01/2008-12/30/2008,(PI)
6. HIV/AIDS awareness and life skills education for delinquent children in Work-study schools, Supported by funds from Social Mobilization Fund of Prevention and Cure by China State Council Grants 08-Ⅰ-39，01/01/2009-12/30/2009 (PI)
7. Comprehensive intervention model and early warning system on poor vision of primary and middle school students in wuhan city,Supported by funds fromWuhan key program foundationof science and technology(PI)
Career goals
1.Molecular epidemiology of head and neck squamous cell carcinoma
2.Carcinogenesis and biomarkers of occupational and environmental related cancer
3.Comprehensive intervention model, early warning, and health management on poor vision of primary and middle school students
i- Publications in peer-reviewed journals (in English)
1 Shi H, Chen J, Li Y, Li G, Zhong R, Du D, Meng R, Kong W, Lu M*: Identification of a six microrna signature as a novel potential prognostic biomarker in patients with head and neck squamous cell carcinoma. Oncotarget 2016(*Corresponding Author)
2 Meng RW, Li YC, Chen X, Huang YX, Shi H, Du DD, Niu X, Lu C, Lu MX*: Aberrant methylation of rassf1a closely associated with hnscc, a meta-analysis. Scientific reports 2016;6:20756.(*Corresponding Author)
3 Shi H, Chen X, Lu C, Gu C, Jiang H, Meng R, Niu X, Huang Y, Lu M*: Association between p16ink4a promoter methylation and hnscc: A meta-analysis of 21 published studies. PloS one 2015;10:e0122302.(*Corresponding Author)
4 Gu C, Lu J, Cui T, Lu C, Shi H, Xu W, Yuan X, Yang X, Huang Y, Lu M*: Association between mgmt promoter methylation and non-small cell lung cancer: A meta-analysis. PloS one 2013;8:e72633.(*Corresponding Author)
5 Shi H, Li Y, Wang X, Lu C, Yang L, Gu C, Xiong J, Huang Y, Wang S, Lu M*: Association between rassf1a promoter methylation and ovarian cancer: A meta-analysis. PloS one 2013;8:e76787.(*Corresponding Author)
6 Lu M, Liu Z, Yu H, Wang LE, Li G, Sturgis EM, Johnson DG, Wei Q: Combined effects of e2f1 and e2f2 polymorphisms on risk and early onset of squamous cell carcinoma of the head and neck. Molecular carcinogenesis 2012;51 S1:E132-141.
7 Lu M, Lu J, Yang X, Yang M, Tan H, Yun B, Shi L: Association between the nbs1 e185q polymorphism and cancer risk: A meta-analysis. BMC cancer 2009;9:124.
8 Huang Y, Yan C, Yin P, Lu M: A mixture of hierarchical joint models for longitudinal data with heterogeneity, non-normality, missingness, and covariate measurement error. Journal of biopharmaceutical statistics 2016;26:299-322.
9 Zhang SL, Leng Y, Liu B, Shi H, Lu M, Kong WJ: Meniett therapy for meniere’s disease: An updated meta-analysis. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 2016;37:290-298.
10 Kong W, Niu X, Zeng T, Lu M, Chen L: Impact of treatment with metformin on adipocytokines in patients with polycystic ovary syndrome: A meta-analysis. PloS one 2015;10:e0140565.
11 Zhang S, Leng Y, Liu B, Shi H, Lu M, Kong W: Diagnostic value of vestibular evoked myogenic potentials in endolymphatic hydrops: A meta-analysis. Scientific reports 2015;5:14951.
12 Chen X, Niu X, Xiao Y, Dong J, Lu M, Kong W: Effect of continuous positive airway pressure on leptin levels in patients with obstructive sleep apnea: A meta-analysis. Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2015;152:610-618.
13 Xiong J, Li Y, Huang K, Lu M, Shi H, Ma L, Luo A, Yang S, Lu Z, Zhang J, Yang L, Wang S: Association between dapk1 promoter methylation and cervical cancer: A meta-analysis. PloS one 2014;9:e107272.
14 Niu X, Chen X, Xiao Y, Dong J, Zhang R, Lu M, Kong W: The differences in homocysteine level between obstructive sleep apnea patients and controls: A meta-analysis. PloS one 2014;9:e95794.
i- Publications in refereed journals (in Chinese)
1. Ke F, Yu YZ, Yang LH, Lu BL, Zheng WG, Jia J, Yan J, Shi LY, Lu MX*. Development and evaluation of a vision-ralated life quality scale for middle school students. Chin J Public Health. 2013; 29(4):551-553.(*Corresponding Author)
2. Yuan XL, Zhuo ZP, Wang J, Liu XL, Lu MX* and Xu J*. Relationship between the body mass index, waist circumference and lipids levels among adults in Shenzhen. JOURNAL OF HYGIENE RESEARCH. 2013; 42(3):360-363+368. (*Corresponding Author)
3. Xu WM, Zhong R, Rui R, Zou L, Chen W, Duan SY, Zhu BB, Zheng XW, Miao XP, Lu MX*. Relationship between STK15 Phe31Ile polymorphism and risk of breast cancer: a Meta-analysis. Chinese Journal of Birth Health & Heredity. 2011; 19(10):19-21. (*Corresponding Author)
4. Liu JQ, Du YK, Yang LH, Shi LY, Lu BL, Yan J,Lu MX*. Analysis on status of poor vision among primary and middle school students. Chinese Journal of School Health. 2011; 32(1):73-74. (*Corresponding Author)
5. Lu MX, Yang LH, Lu BL, Cao HW, Gong J, Jia J, Yan J and Shi LY. Comparison of intervention effects on myopia by different methods among students Chinese Journal of School Health. 2011; 32(4):459-461.
6. Lu MX, Yang LH, Lu BL, Cao HW, Gong J, Jia J, Yan J and Shi LY. Effect evaluation of different intervention methods for prevention and control of poor eyesight in primary and secondary students. Chin J Dis Control Prev. 2010; 14(9):878-881.
7. Lu MX, Yang XB, Bai Y and Wu TC. Model of Lung Cancer Risk with Single Nucleotide Polymorphism in the DNA Damage Binding Protein 2. J Environ Occup Med. 2008; 25(5):420-424.
8. Lu MX, Shi LY, Lu BL, Yang LH, Yan J and Wu M. Cross-sectional Investigation of Eyesight Dysfunction among Key Middle School Students in Wuhan. Occup and Health. 2008; 24(15):1562-1564.
9. Lu MX, Shi LY, Lu BL, Yang LH, Yan J and Wu M. Analysis on influencing factors of key middle school students’ eyesight dysfunction in Wuhan City. Chin J Dis Control Prev. 2008; 12(4):354-356.
10. Lu MX, Yang XB, Bai Y, He YF, Shi LY and Wu TC. Association of genetic polymorphisms in the DNA repair gene DDB2 with risk of lung cancer. Chin J Dis Control Prev. 2007; 11(5):444-447.
11. Lu MX, Duan QH, Shi LY, Gu Y, Zhang HJ and Ran P. Study on the factors influencing the quality of life among patients with malignant lymphoma Chin j Epidemiol. 2006; 27(6):535-539.
12. Lu MX, Gu Y, Shi LY, Zhang HJ, Ran P and Xiang LY. Quality of life questionnaire assessment in patients with malignant lymphoma. Chinese Journal of Clinical Rehabilitation. 2004; 8(2):214-215.
13. Zhang YK, Lu MX*, Shi LY, Zhang HJ, Lu BL, Yang LH, Yan J, Rui Q, Yan Q, Huang HM and Wu Q. Relationship between near vision habit and low vision of students of a middle school in Wuhan. Central China Medical Journal. 2006; 30(5):389-391. (*Corresponding Author)
14. Lu MX, Shi LY and Xiong GL. Reflections on SARS. Medicine and Society. 2004; 17(1):13-14+18.
15. Dong YB, Wang ZZ, Shi LY, Hu XY,Lu MX*. Effect Evaluation on Health Education of AIDS Prevention among Drug Addicts in Correctional Center. Occup and Health. 2008; 24(19):2006-2008. (*Corresponding Author)
16. Mo HY, Chen H, Lu MX, Yu HP, Yang NN, Fang Y, Duan JJ and Shi LY. Integrated analysis of effects of life style on incidence of malignant tumor. Chin J Public Health. 2003; 19(4):407-408.
17. Duan QH, Zhang JR, Nie SF, Lu MX, Wu TC, Xiong GL, Lu YX, Shi LY. Public health emergency response capacity on evaluation of primary disease prevention and control mechanism in Hubei. Chin J Epidemiol. 2003; 24(12):1077.
18. Shi LY and Lu MX. Revelation of SARS. Chin J Pharmacoepidemiol. 2003; 12(4):176-178.
19. Gu Y, Yuan J, Wu XX, Wang XJ, Shi LY, Lu MX, Zhang HJ and Duan QH. Study on the Deletion of RB Gene and Its Relationship to Risk Factors in Chinese Female Breast Cancer. CHINA PUBLIC HEALTH. 2000; 16(10):284-285.
