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Chaolong Wang

Research Interests

Population genetics, statistical genetics/genomics, disease gene mapping, integrative genomics, next-generation sequencing data analysis, high dimensional data analysis


Academic Appointments

  • 2018-Present: Professor, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

  • 2015-2018: Senior Research Scientist, Genome Institute of Singapore, Agency of Science Technology and Research (A*STAR), Singapore

  • 2016-2018: Adjunct Assistant Professor, Duke-National University of Singapore Medical School, Singapore


Training and Education

  • 2012-2014: Research Fellow, Biostatistics, Harvard School of Public Health, Boston, MA, USA

  • 2008-2012: Ph.D. in Bioinformatics, University of Michigan, Ann Arbor, MI, USA

  • 2008-2011: M.S. in Bioinformatics, University of Michigan, Ann Arbor, MI, USA

  • 2008-2011: M.A. in Statistics, University of Michigan, Ann Arbor, MI, USA

  • 2004-2008: B.S. in Physics, Peking University, Beijing, China


Honors and Awards


  • 2013 Charles J. Epstein Award semifinalist, American Society of Human Genetics

  • 2012 Stellar Abstract Award in the 6th Annual PQG Conference, Harvard University

  • 2011 International Student Research Fellowship, Howard Hughes Medical Institute

  • 2011 Rackham Predoctoral Fellowship, University of Michigan

  • 2011 DeLill Nasser Award, Genetics Society of America


  • 2008 Program in Biomedical Sciences Fellowship, University of Michigan


Selected Publications (* Co-first author; # Corresponding author)

  1. D Wu*, J Dou*, X Chai*, C Bellis, A Wilm, CC Shih, WWJ Soon, N Bertin, CB Lin, CC Khor, M DeGiorgio, S Cheng, L Bao, N Karnani, WYK Hwang, S Davila, P Tan, A Shabbir, A Moh, EK Tan, JN Foo, LL Goh, KP Leong, RSY Foo, CSP Lam, AM Richards, CY Cheng, T Aung, TY Wong, HH Ng, SG10K Consortium, J Liu#, C Wang#. Large-scale whole-genome sequencing of three diverse Asian populations in Singapore. Cell. 2019; 179(3): 736-749. (Cover Article of Cell)

  2. J Dou*, B Sun*, X Sim, JD Hughes, DF Reilly, ES Tai, J Liu, C Wang#. Estimation of kinship coefficient in structured and admixed populations using sparse sequencing data. PLoS Genetics. 2017; 13: e1007021.

  3. D Taliun, S Chothani, S Schonherr, L Forer, M Boehnke, GR Abecasis, C Wang#. LASER server: ancestry tracing with genotypes or sequence reads. Bioinformatics. 2017; 33: 2056-2058.

  4. H Chen*, C Wang*, MP Conomos, AM Stilp, Z Li, T Sofer, AA Szpiro, W Chen, JM Brehm, JC Celedon, S Redline, GJ Papanicolaou, TA Thornton, CC Laurie, K Rice, X Lin. Control for population structure and relatedness for binary traits in genetic association studies via logistic mixed models. American Journal of Human Genetics. 2016; 98: 653-666.

  5. C Wang#, X Zhan, L Liang, GR Abecasis, X Lin. Improved ancestry estimation for both genotyping and sequencing data using projection Procrustes analysis and genotype imputation. American Journal of Human Genetics. 2015; 96: 926-937.

  6. C Wang#, X Zhan, J Bragg-Gresham, HM Kang, D Stambolian, E Chew, K Branham, J Heckenlively, The FUSION Study, RS Fulton, RK Wilson, ER Mardis, X Lin, A Swaroop, S Zollner, GR Abecasis#. Ancestry estimation and control of population stratification for sequence-based association studies. Nature Genetics. 2014; 46: 409-415.

  7. X Zhan*, DE Larson*, C Wang*, DC Koboldt, Y Sergeev, 52 other coauthors, ER Mardis, A Swaroop, GR Abecasis. Identification of a rare coding variant in Complement 3 associated with age-related macular degeneration. Nature Genetics. 2013; 45: 1375-1379

  8. C Wang#, KB Schroeder, NA Rosenberg. A maximum-likelihood method to correct for allelic dropout in microsatellite data with no replicate genotypes. Genetics. 2012; 192: 651-669.

  9. C Wang#, S Zollner, NA Rosenberg. A quantitative comparison of the similarity between genes and geography in worldwide human populations. PLoS Genetics. 2012; 8: e1002886

  10. C Wang, ZA Szpiech, J Degnan, M Jakobsson, TJ Pemberton, JA Hardy, AB Singleton, NA Rosenberg. Comparing spatial maps of human population-genetic variation using Procrustes analysis. Statistical Applications in Genetics and Molecular Biology. 2010; 9: Article 13