首页  > 师资队伍  > 院系教师  > 教师简介  > 正文

钟荣

  • 中文简历English resume

  • 姓名:钟荣


  • 职务:博士,副教授,博士生导师

  • 院系:流行病与卫生统计学系

  • 地址:湖北省武汉市航空路13号 430030

  • 电话:86-27-83690744

  • 邮箱:zhongr@hust.edu.cn



主要研究方向

    乙型肝炎、肝癌和乳腺癌的分子流行病学研究,对影响恶性肿瘤发生和发展的内在遗传因素以及环境因素进行了较深入的探讨。先后承担国家自然科学基金面上项目、国家自然科学基金青年项目、省部级和校级项目多项。以通讯作者和第一作者在国际专业杂志发表SCI论文24篇(其中影响因子5分以上10篇,包括一篇ESI高被引论文),总被引频次达270余次,H因子为12。获湖北省自然科学奖二等奖,华中学者晨星岗,湖北省优秀博士学位论文、裘法祖奖学金等奖项。


主要负责的科研项目

1.LncRNAs调控型遗传变异与中国人群肝癌易感性及机制研究,国家自然科学基金(面上项目),时间:2019-2022,经费:58万元

2.基于大数据的肿瘤风险预测模型在前瞻性队列人群中的验证研究, 国家重点研发计划“重大慢性非传染性疾病防控研究”专项子课题, 时间:2016-2020,分拨经费:10万元

3.FOXA1先锋转录因子靶基因结合区遗传变异与乳腺癌易感性的关系及机制研究,国家自然科学基金(青年项目), 时间:2015 -2017,经费:23万元

4.叉头框A蛋白靶基因结合区遗传变异与肝癌易感性研究,中国博士后科学基金会,时间:2013-2015,经费:8万元

5.乙肝病毒受体分子遗传多态与HBV易感性的研究,经费来源:中国博士后科学基金会,时间:2014-2016,经费:15万元

6.TGF-β信号通路关键基因低频遗传变异与结直肠癌易感性研究,经费来源:华中科技大学自主创新研究基金,时间:2015-2016,经费:5万元


代表性论著

1. Chang J, Zhong R, Tian J, Li J, Zhai K, Ke J, Lou J, Chen W, Zhu B, Shen N, Zhang Y, Zhu Y, Gong Y, Yang Y, Zou D, Peng X, Zhang Z, Zhang X, Huang K, Wu T, Wu C*, Miao X*, Lin D. Exome-wide analyses identify low-frequency variant in CYP26B1 and additional coding variants associated with esophageal squamous cell carcinoma. Nat Genet, 50(3):338-343, 2018. (co-first author)


2. Zhang Y, Yang B, Cheng X, Liu L, Zhu Y, Gong Y, Yang Y, Tian J, Peng X, Zou D, Yang L, Mei S, Wang X, Lou J, Ke J, Li J, Gong J, Chang J, Yuan P*, Zhong R*. Integrative functional genomics identifies regulatory genetic variant modulating RAB31expression and altering susceptibility to breast cancer. Mol Carcinog, 2018. https://doi.org/10.1002/mc.22902. (*Corresponding author)


3. Chang J, Tian J, Zhu Y, Zhong R, Zhai K, Li J, Ke J, Han Q, Lou J, Chen W, Zhu B, Shen N, Zhang Y, Gong Y, Yang Y, Zou D, Peng X, Zhang Z, Zhang X, Huang K, Yang M, Wang L, Wu C*, Lin D*, Miao X*. Exome-wide analysis identifies three low-frequency missense variants associated with pancreatic cancer risk in Chinese populations. Nat Commun, 9, 3688, 2018. (co-first author)


4. Chang J, Tian J, Yang Y, Zhong R, Li J, Zhai K, Ke J, Lou J, Chen W, Zhu B, Shen N, Zhang Y, Gong Y, Zhu Y, Zou D, Peng X, Huang K, Miao X*. A rare missense variant in TCF7L2 associates with colorectal cancer risk by interacting with a GWAS-identified regulatory variant in the MYC enhancer. Cancer Res, 78(17), 5164-5172, 2018. (co-first author)


5. Li J, Wang Y, Zhu Y, Gong Y, Yang Y, Tian J, Zhang Y, Zou D, Peng X, Ke J, Gong J, Zhong R*, Chang J*. Breast cancer risk-associated variants at 6q25.1 influence risk of hepatocellular carcinoma in a Chinese population. Carcinogenesis 38(4):447-454, 2017. (*Corresponding author)


6. Chen X, Wang Y, Cheng K, Li J, Lou J, Ke J, Yang Y, Gong Y, Zhu Y, Wang L*, Zhong R*. Genetic variants in the regulatory region of SLC10A1 are not associated with the risk of hepatitis B virus infection and clearance. Infection, Genetics and Evolution 44: 495-500, 2016. (*Corresponding author)


7. Zhang Y, Li Y, Jiang S, Chen W, Lou J, Ke J, Li J, Zhu Y, Gong Y, Yang Y, Tian J, Peng X, Zou D, Gong J, Chang J, Miao X*, Zhong R*. A functional variant rs4442975 modulating FOXA1-binding affinity does not influence the risk or progression of breast cancer in Chinese Han population. Oncotarget 7(49): 81691-81697, 2016. (*Corresponding author)


8. Chen X, Wu F, Liu Y, Lou J, Zhu B, Zou L, Chen W, Gong J, Wang Y*, Zhong R*. The contribution of serum hepatitis B virus load in the carcinogenesis and prognosis of hepatocellular carcinoma: evidence from two meta-analyses. Oncotarget 7(31): 49299-49309, 2016. (*Corresponding author)


9. Zhong R, Liu L, Zou L, Sheng W, Zhu B, Xiang H, Chen W, Chen J, Rui R, Zheng X, Yin J, Duan S, Yang B, Sun J, Lou J, Xie D, Xu Y, Nie S*, Miao X*. Genetic variations in the TGFbeta signaling pathway, smoking and risk of colorectal cancer in a Chinese population. Carcinogenesis, 34(4), 936-942, 2013.


10. Zhong R, Chen X, Zhu B, Lou J, Li J, Shen N, Yang Y, Gong Y, Zhu Y, Yuan J, Xia X*, Miao X*. MAD1L1 Arg558His and MAD2L1 Leu84Met interaction with smoking increase the risk of colorectal cancer. Sci Rep 5:12202, 2015. (IF 5.578)


11. Zhu B, Zou L, Qi L, Zhong R*, Miao X*. Allium Vegetables and Garlic Supplements do Not Reduce Risk of Colorectal Cancer, Based on Meta-analysis of Prospective Studies. Clin Gastroenterol Hepatol 2014. Mar 26. pii: S1542-3565(14)00451-0. (*Corresponding author)


12. Zhong R, Liu L, Tian Y, Wang Y, Tian J, Zhu B, Chen W, Qian J, Zou L, Xiao M, Shen N, Yang H, Lou J, Qiu Q, Ke J, Lu X, Wang Z, Song W, Zhang T, Li H, Wang L*, Miao X*. Genetic variant in SWI/SNF complexes influences hepatocellular carcinoma risk: a new clue for the contribution of chromatin remodeling in carcinogenesis. Sci Rep, 4,  4147, 2014.


13. Zhong R, Liu L, Zou L, Zhu Y, Chen W, Zhu B, Shen N, Rui R, Long L, Ke J, Lu X, Zhang T, Zhang Y, Wang Z, Sun Y, Cheng L, Miao X*. Genetic variations in TERT-CLPTM1L locus are associated with risk of lung cancer in Chinese population. Mol Carcinog, 52 Suppl 1, E118-126, 2013.


14. Zhong R, Yang B, Tang H, Zou L, Song R, Zhu L*, Miao X*. Meta-analysis of the association between DCDC2 polymorphisms and risk of dyslexia. Mol Neurobiol, 47(1), 435-442, 2013.


15. Zhong R, Tian Y, Liu L, Qiu Q, Wang Y, Rui R, Yang B, Duan S Y, Shi J, Miao X*, Wang L*, Li H. HBV-related hepatocellular carcinoma susceptibility gene KIF1B is not associated with development of chronic hepatitis B. PLoS One, 7(2), e28839, 2012. 


16. Chen W, Song H, Zhong R, Zhu B, Guo H, Lou J, Shen N, Li J, Chen X, Liu C, Ming J, Huang T*, Miao X*. Risk of GWAS-identified genetic variants for breast cancer in a Chinese population: A multiple interaction analysis. Breast Cancer Res Treat, 142(3), 637-644, 2013. (co-first author)


17. Li J, Zou L, Chen W, Zhu B, Shen N, Ke J, Lou J, Song R, Zhong R*, Miao X*. Dietary mushroom intake may reduce the risk of breast cancer: evidence from a meta-analysis of observational studies. PLoS One 2014;9: e93437. (*Corresponding author)


18. Zhang X, Zhong R, Zhang Z, Yuan J, Liu L, Wang Y, Kadlubar S, Feng F, Miao X*. Interaction of cyclooxygenase-2 promoter polymorphisms with helicobacter pylori infection and risk of gastric cancer. Mol Carcinog, 50(11), 876-883, 2011. (co-first author)


19. Liu C, Zhong R, Lou J, Pan A, Tang Y, Chang J, Ke J, Li J, Yuan J, Wang Y, Chen W, Guo H, Wei S, Liang Y, Zhang X, He M, Hu FB, Wu T, Yao P, Miao X (2016) Nighttime sleep duration and risk of nonalcoholic fatty liver disease: the Dongfeng-Tongji prospective study. Annals of Medicine, 48(6): 468-476, 2016. (Co-first authors)


20. Zhang X, Zhong R, Liu L, Wang Y, Yuan J, Wang P, Sun C, Zhang Z, Song W, Miao X*. Smoking and cox-2 functional polymorphisms interact to increase the risk of gastric cardia adenocarcinoma in chinese population. PLoS One, 6(7), e21894, 2011. (co-first author)


21. Liu L, Zhong R, Zou L, Fu J, Zhu B, Chen W, Ye X, Gao Y, Yang Y, Christiani D. C. Chen S, Miao X. Variants in the 5'-upstream region of GPC5 confer risk of lung cancer in never smokers. Cancer Epidemiol, 38(1):66-72, 2014. (co-first author)


22. Yang J, Duan S, Zhong R, Yin J, Pu J, Ke J, Lu X, Zou L, Zhang H, Zhu Z, Wang D, Xiao H, Guo A, Xia J, Miao X*, Tang S*, Wang G*. Exome sequencing identified nrg3 as a novel susceptible gene of hirschsprung's disease in a Chinese population. Mol Neurobiol, 47(3), 957-966, 2013. (co-first author)


23. Liu L, Wu J, Zhong R, Wu C, Zou L, Yang B, Chen W, Zhu B, Duan S, Yu D, Tan W, Nie S*, Lin D*, Miao X*. Multi-loci analysis reveals the importance of genetic variations in sensitivity of platinum-based chemotherapy in non-small-cell lung cancer. Mol Carcinog, 52(12), 923-931, 2013. (co-first author)


24. Han W, Zhou Y, Zhong R, Wu C, Song R, Liu L, Zou L, Qiao Y, Zhai K, Chang J, Huang L, Lu X, Lou J, Yu D, Tan W, Zhang J, Wang H*, Miao X*. Functional polymorphisms in fas/fasl system increase the risk of neuroblastoma in chinese population. PLoS One, 8(8), e71656, 2013. (co-first author)


25. 陈伟, 张怡, 朱颖, 杨洋, 龚雅洁, 缪小平, 钟荣. p53靶基因结合区遗传变异与中国人群乳腺癌遗传易感性的关联研究. 中华流行病学杂志, 2016; 37(8): 1063-1068.(通讯作者)


26.陈雪琴, 王英, 娄娇, 杨洋, 龚雅洁, 朱颖, 向成, 钟荣. MicroRNA-122结合区遗传变异IL-1A rs3783553与慢性HBV感染的关联研究. 华中科技大学学报(医学版) 2016:53-55+69.(通讯作者)