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刘莉

  • 中文简历English resume

  • 姓名:刘莉

  •  

  • 职务:博士,副教授,博士生导师

  • 院系:流行病与卫生统计学系

  • 地址:湖北省武汉市航空路13号 430030

  • 电话:86-27-83693763

  • 邮箱:gracefulliuly@163.com

 

       2007年毕业于华中科技大学预防医学专业,2012年在华中科技大学同济医学院获医学博士学位。现为华中科技大学公共卫生学院副教授,博士生导师。2016.1-2017.12在哈佛大学医学院Dana-Farber Cancer Institute及哈佛大学公共卫生学院做博士后研究。主要研究方向:肿瘤分子流行病学。已发表SCI论文近30篇,总IF超过160分,其中以第一作者、并列第一作者或通讯作者在Gastroenterology, Gut, Clin Gastroenterol Hepatol, MolCarcinog, Eur J Epidemiol, Br J Sports Med, Cancer, Breast Cancer Res Treat等杂志上发表论文20篇。获得湖北省科技进步二等奖(第二完成人)。现担任Clinical Cancer Research, PLoS One 等杂志的审稿人。

 

 

 

主要承担和参与的科研项目

2014-2016 全基因组表达相关拷贝数变异在结直肠癌发生发展中的作用及机制研究,国家自然基金青年基金 (81302491)

2014-2016 全基因组表达相关拷贝数变异在结直肠癌易感性中的作用,教育部博士点课题

2013-2014 端粒酶基因多态性、端粒长度在胆囊癌易感性中的作用,校自助创新课题(2013QN001)

2010-2015中国农村地区传染病整合监测系统:为资源匮乏地区疾病流行的早期发现收集证据,欧盟第七框架计划项目 (241900)

2015-2019线粒体动力学改变在氟神经毒性中的作用及白藜芦醇干预效果研究,国家自然基金重点项目 (81430076)

2014-2017遗传易感性和早期生活方式的交互作用在婴儿肥胖发生中的作用,国家自然基金面上项目 (81373017)

2012-2015 Wnt信号通路及其关键靶基因与结直肠癌遗传易感性的关联研究,国家自然基金面上项目 (81172752)

2012-2014 妊娠期骨骼铅动员的MTFHRVDR基因多态性及相关因素研究,国家自然基金青年基金 (81102185)

2012-2014 钾离子信号网络基因遗传变异与注意缺陷多动障碍易感性研究,国家自然基金青年基金 (81101016)

 

 

 

 

代表性论著

1. Liu L, Nishihara R, Qian ZR, Tabung FK, Nevo D, Zhang X, Song M, Cao Y, Mima K, Masugi Y, Shi Y, da Silva A, Twombly T, Gu M, Li W, Hamada T, Kosumi K, Inamura K, Nowak JA, Drew DA, Lochhead P, Nosho K, Wu K, Wang M, Garrett WS, Chan AT, Fuchs CS, Giovannucci EL, Ogino S. Association Between Inflammatory Diet Pattern and Risk of Colorectal Carcinoma Subtypes Classified by Immune Responses to Tumor. Gastroenterology. 2017 Dec;153(6):1517-1530.e14.

2. Yang W, Liu L, Masugi Y, Qian ZR, Nishihara R, Keum N, Wu K, Smith-Warner S, Ma Y, Nowak JA, Momen-Heravi F, Zhang L, Bowden M, Morikawa T, Silva AD, Wang M, Chan AT, Fuchs CS, Meyerhardt JA, Ng K, Giovannucci E, Ogino S, Zhang X. Calcium intake and risk of colorectal cancer according to expression status of calcium-sensing receptor (CASR). Gut. 2017 Jul 4.pii: gutjnl-2017-314163. doi: 10.1136/gutjnl-2017-314163. [Epub ahead of print] (co-first author)

3. Liu L, Tabung FK, Zhang X, Nowak JA, Qian ZR, Hamada T, Nevo D, Bullman S, Mima K, Kosumi K, da Silva A, Song M, Cao Y, Twombly TS, Shi Y, Liu H, Gu M, Koh H, Li W, Du C, Chen Y, Li C, Li W, Mehta RS, Wu K, Wang M, Kostic AD, Giannakis M, Garrett WS, Hutthenhower C, Chan AT, Fuchs CS, Nishihara R, Ogino S, Giovannucci EL. Diets That Promote Colon Inflammation Associate With Risk of Colorectal Carcinomas That Contain Fusobacterium nucleatum. Clin Gastroenterol Hepatol. 2018 Apr 24. pii: S1542-3565(18)30389-6. doi: 10.1016/j.cgh.2018.04.030. [Epub ahead of print]

4. Liu L, Nevo D, Nishihara R, Cao Y,Song M, Twombly TS, Chan AT, Giovannucci EL, VanderWeele TJ, Wang M, Ogino S.Utility of inverse probability weighting in molecular pathological epidemiology. Eur J Epidemiol. 2017 Dec 20.doi: 10.1007/s10654-017-0346-8. [Epub ahead of print](co-first author)

5. Li T, Wei S, Shi Y, Pang S, Qin Q, Yin J, Deng Y, Chen Q, Wei S, Nie S, Liu L. The dose-response effect of physical activity on cancer mortality: findings from 71 prospective cohort studies. Br J Sports Med. 2016 Mar;50(6):339-45.

6. Liu L, Shi Y, Li T, Qin Q, Yin J, Pang S, Nie S, Wei S. Leisure time physical activity and cancer risk: evaluation of the WHO's recommendation based on 126 high-quality epidemiological studies. Br J Sports Med. 2016 Mar;50(6):372-8.

7. Liu L, Wu J, Wu C, Zhong R, Zhang X, Tan W, Nie S, Miao X, Lin D. A functional polymorphism (-1607 1G→2G) in the matrix metalloproteinase-1 promoter is associated with development and progression of lung cancer. Cancer. 2011 Nov 15;117(22):5172-81.

8. Liu L, Huang J, Wang K, Li L, Li Y, Yuan J, Wei S. Identification of hallmarks of lung adenocarcinoma prognosis using whole genome sequencing. Oncotarget. 2015 Nov 10;6(35):38016-28.

9. Shi Y, Li T, Wang Y, Zhou L, Qin Q, Yin J, Wei S, Liu L, Nie S. Household physical activity and cancer risk: a systematic review and dose-response meta-analysis of epidemiological studies. Sci Rep. 2015 Oct 7;5:14901. (co-corresponding author)

10. Liu L, Wu J, Zhong R, Wu C, Zou L, Yang B, Chen W, Zhu B, Duan S, Yu D, Tan W, Nie S, Lin D, Miao X. Multi-loci analysis reveals the importance of genetic variations in sensitivity of platinum-based chemotherapy in non-small-cell lung cancer. Mol Carcinog. 2013 Dec;52(12):923-31.

11. Liu L, Yuan P, Liu L, Wu C, Zhang X, Guo H, Zhong R, Xu Y, Wu J, Duan S, Rui R, Wu T, Nie S, Miao X, Lin D. A functional -77T>C polymorphism in XRCC1 is associated with risk of breast cancer. Breast Cancer Res Treat. 2011 Jan;125(2):479-87.

12. Chen D, Liu L, Xiao Y, Peng Y, Yang C, Wang Z. Ethnic-specific meta-analyses of association between the OPRM1 A118G polymorphism and alcohol dependence among Asians and Caucasians. Drug and Alcohol Dependence. 2012 Jun 1;123(1-3):1-6. (Co-first author)

13. Liu L, Zhong R, Wei S, Xiang H, Chen J, Xie D, Yin J, Zou L, Sun J, Chen W, Miao X, Nie S. The leptin gene family and colorectal cancer: interaction with smoking behavior and family history of cancer. PLoS One. 2013 Apr 8;8(4):e60777.

14. Liu L, Zhong R, Wei S, Yin J, Xiang H, Zou L, Chen W, Chen J, Zheng X, Huang L, Zhu B, Chen Q, Duan S, Rui R, Yang B, Sun J, Xie D, Xu Y, Miao X, Nie S. Interactions between Genetic Variants in the Adiponectin, Adiponectin Receptor 1 and Environmental Factors on the Risk of Colorectal Cancer. PLoS One. 2011;6(11):e27301.

15. Qin Q, Liu L, Zhong R, Zou L, Yin J, Zhu B, Cao B, Chen W, Chen J, Li X, Li T, Lu X, Lou J, Ke J, Wei S, Miao X, Nie S. The genetic variant on chromosome 10p14 is associated with risk of colorectal cancer: results from a case-control study and a meta-analysis. PloS One. 2013 May 22;8(5):e64310. (co-first author)

16. Zhou L, Yu L, Wang Y, Lu Z, Tian L, Tan L, Shi Y, Nie S, Liu L. A hybrid model for predicting the prevalence of schistosomiasis in humans of Qianjiang City, China.PLoS One. 2014;9(8):e104875.

17. Fan Y, Yang M, Jiang H, Wang Y, Yang W, Zhang Z, Yan W, Diwan VK, Xu B, Dong H, Palm L, Liu L, Nie S. Estimating the effectiveness of early control measures through school absenteeism surveillance in observed outbreaks at rural schools in Hubei, China. PLoS One. 2014 Sep 24;9(9):e106856. (co-corresponding author)

18. Jiang H, Xie N, Cao B, Tan L, Fan Y, Zhang F, Yao Z, Liu L, Nie S. Determinants of Progression to AIDS and Death Following HIV Diagnosis: A Retrospective Cohort Study in Wuhan, China. PLoS One. 2013 Dec 23;8(12):e83078. (co-corresponding author)

19. Li T, Shi Y, Yin J, Qin Q, Wei S, Nie S, Liu L. The association between lipid metabolism gene polymorphisms and nephropathy in type 2 diabetes: a meta-analysis. Int Urol Nephrol. 2015 Jan;47(1):117-30.

20. Pang S, Zhou Z, Yu X, Wei S, Chen Q, Nie S, Liang X, Liu L.The predictive value of integrated inflammation scores in the survival of patients with resected hepatocellular carcinoma: A Retrospective Cohort Study. Int J Surg. 2017 Jun;42:170-177.