首页 > 师资队伍 > 院系教师 >

袁晶

  • 中文简历English resume
  • 姓名:袁晶
  • 职务:教授,博士生导师,环境与健康研究平台主任
  • 院系:劳动卫生与环境卫生学系
  • 地址:
  • 电话:
  • 邮箱:jyuan@tjh.tjmu.edu.cn

学历

医学学士:1983年,原同济医科大学公共卫生学院
医学硕士:2001年,华中科技大学同济医学院公共卫生学院
医学博士:2003年,Ulm University, Germany

 

工作经历

1983-1987 中山医科大学公共卫生学院卫生统计学教研室

1987-1992 原同济医科大学公共卫生学院环境卫生学教研室

1992-1994 访问学者,Center for Advanced Biotechnology and Medicine, UMDNJ-Robert Wood Johnson Medical School, NJ, USA

1995-1999 原同济医科大学公共卫生学院环境卫生学教研室

1999-1999 访问学者,Charité Campus Virchow-Klinikum,Universitätsmedizin Berlin, Humbold University of D-Berlin, Berlin,Germany

2000-2001 华中科技大学同济医学院公共卫生学院环境卫生学教研室

2002-2003 学生学者,Charité Campus Virchow-Klinikum,Universitätsmedizin Berlin, Humbold University of D-Berlin, Berlin,Germany

2004-2005 华中科技大学同济医学院公共卫生学院环境卫生学教研室

2005-present 华中科技大学同济医学院公共卫生学院劳动卫生与环境卫生学系

 

在研项目

1. 国家自然科学基金面上项目: Sirtuins参与TCEP致细胞损伤的线粒体调控机制研究.(项目编号:81273023, 2013-2016.12)。

 

2. 国家自然科学基金面上项目:SEC14L3激活PI3K/Akt信号通路调控BaP与DEHP致细胞损伤的机制研究. (项目编号:81472947,2015-2018)”

 

3. 环保公益项性行业科研专项“典型区域细颗粒物污染特征与人群健康风险预警指标体系研究”课题(项目编号:201409081)

 

研究领域

• 环境重要污染物(颗粒物、多环芳烃、增塑剂等)暴露水平及其人群健康危害研究

 

• 环境重要有机污染物(B[a]P、DEHP、MEHP、TCEP)的分子毒性机制研究

 

近期发表论文

1. Zhang W, Zhang Y, Xu T, Wang Z, Wang J, Xiong W, Lu WH, Zheng H, Yuan J*. Involvements of ROS-mediated mitochondrial dysfunction and SIRT3 down-regulation in tris(2-chloroethyl)phosphate-induced cell cycle arrest. Toxicol Res. 2016, 5, 461-470

 

 

2. Zhou Y†, Sun H†, Xie J, Song Y, Liu Y, Huang X, Zhou T, Rong Y, Wu T, Yuan J*, Chen W*. Urinary Polycyclic Aromatic Hydrocarbon Metabolites and Altered Lung Function in Wuhan, China. Am J Respir Crit Care Med. 2015 Dec 4. [Epub ahead of print]

 

3. Hou J†, Sun H†, Xiao L, Zhou Y, Yin WJ, Xu T, Cheng J, Chen W*, Yuan J*. Combined effect of urinary monohydroxylated polycyclic aromatic hydrocarbons and impaired lung function increased risk of diabetes. Envrion Res (Accepted)

 

4. Hou F†, Huang X†, Liu C†, Sun H, Zhou T, Song Y, Rong Y, Zhu B, Chen W, Wang J, Wang J, He M, Miao X, Hoffmann B, Wu T, Chen W*, Yuan J*. Housing characteristics in relation to exhaled nitric oxide in China. Am J Health Behav. 2015, 39(1):88-98

 

5. Hou J†, Liu C†, Yao P†, Chen W, He M, Wang Y, Liang Y, Miao X, Wei S, Xu T, Fang W, Zhu J, Li X, Hu FB, Wu T, Yang H*, Yuan J*. Association of Adiposity Indices with Platelet Distribution Width and Mean Platelet Volume in Chinese Adults. PloS One. 2015;10(6):e0129677. doi: 10.1371/journal.pone.0129677.

 

6. Zhang W, Zhang Y, Wang Z, Xu T, Huang C, Yin W, Wang J, Xiong W, Lu W, Zheng H, Yuan J*. Tris-(2-chloroethyl)-phosphate induced cell growth arrest via attenuation of SIRT1-independent PI3K/Akt/mTOR pathway. J Appl Toxicol. 2015, doi: 10.1002/jat.3223

 

7. Yang G, Zhang W, Qin Q, Wang J, Zheng H, Xiong W, Yuan J*. Mono(2-ethylhexyl) phthalate induces apoptosis in p53-silenced L02 cells via activation of both mitochondrial and death receptor pathways. Environ Toxicol. 2015, 30(10):1178-91. doi: 10.1002/tox.21990

 

8. Fang Ye, Xiaoyi Li, Lili Li, Ling Lv, Jing Yuan*, Jun Chen*. The role of Nrf2 in protection against Pb-induced oxidative stress and apoptosis in SH-SY5Y cells. Food Chem Toxicol, 2015, 86:191-201. doi: 10.1016/j.fct.2015.10.009.

 

9. Feng Y†, Huang X, Sun H, Liu C , Zhang B, Zhang Z, Sharma Tengur V, Chen W, Wu T, Yuan J*, Zhang X*. Framingham risk score modifies the effect of PM10 on heart rate variability. Sci Total Environ. 2015, 523:146-51. doi: 10.1016/j.scitotenv.2015.04.009.

 

10. Yang G†, Zhang W†, Qin Q, Wang J, Zheng H, Xiong W, Yuan J*. MEHP induced apoptosis in p53-silenced L02 cells via activations of mitochondrial pathway and death receptor pathways. Environ Toxicol. 2015, 30(10):1178-91. doi: 10.1002/tox.21990.

 

11. Liu C, Yang Y, He M, Yao P, Chen W, Liang Y, Wang Y, Fang W, Zhu J, Li X, Yang H, Yuan J*, Hu FB, Wu T. Passive smoke exposure was related to mean platelet volume in Never-smokers. Am J Health Behav 2014, 38(4):519-528

 

12. Song Y, Hou J, Huang X, Zhang X, Tan A, Rong Y, Sun H, Zhou Y, Cui X, Yang Y, Guo Y, Zhang Z, Luo X, Zhang B, Hou F, He X, Xie J, Wu T, Chen W*, Yuan J. The Wuhan-Zhuhai (WHZH) cohort study of environmental air particulate matter and the pathogenesis of cardiopulmonary diseases: study design, methods and baseline characteristics of the cohort. BMC Public Health. 2014, 14:994. doi: 10.1186/1471-2458-14-994.

 

13. Jiang Y†, Chen X†, Yang G, Wang Q, Wang J, Xiong W, Yuan J*. BaP-induced DNA damage initiated p53-independent necroptosis via the mitochondrial pathway involving Bax and Bcl-2. Hum Exp Toxicol. 2013, 32(12):1245-57. doi: 10.1177/0960327113488613

 

14. Chen X†, Qin Q†, Zhang W, Zhang Y, Zheng H, Liu C, Yang Y, Xiong W, Yuan J*. Activation of the PI3K-AKT-mTOR signaling pathway promotes DEHP-induced Hep3B cell proliferation. Food Chem Toxicol. 2013, 59:325-33. doi: 10.1016/j.fct.2013.06.016.

 

15. Chen X, Wang J, Qin Q, Jiang Y, Yang G, Rao K, Wang Q, Xiong W, Yuan J*. Mono-2-ethylhexyl phthalate induced loss of mitochondrial membrane potential and activation of Caspase3 in HepG2 cells. Environ Toxicol Pharmacol. 2012, 33(3):421-30. doi: 10.1016/j.etap.2012.02.001.

 

16. Yang G, Zhou X, Wang J, Zhang W, Zheng H, Lu W, Yuan J*. MEHP-induced oxidative DNA damage and apoptosis in HepG2 cells correlates with p53-mediated mitochondria-dependent signaling pathway. Food Chem Toxicol. 2012, 50(7):2424-31. doi: 10.1016/j.fct.2012.04.023.

 

编写教材

1. 卫生部“十二五”规划教材、全国高等医药教材建设研究会“十二五”规划教材、全国高等学校教材《预防医学》(供本科护理学类专业用)第3版。2012,北京:人民卫生出版社.(副主编)

 

2. 国家卫生和计划生育委员会“十二五”规划教材、全国高等医药教材建设研究会“十二五”规划教材、全国高等学校教材,供8年制及7年制(“5+3”一体化)临床医学等专业用《预防医学》(第三版).人民卫生出版社.(编委)

 

3. 国家医学电子书包《卫生学》.人民军医出版社.(副主编)

 

4. 全国高等学校医学研究生规划教材《分子毒理学》.人民卫生出版社.(主编)